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  5. ADVANCED CYTOMETRY INSTRUMENTATION SYSTEMS, LLC

ADVANCED CYTOMETRY INSTRUMENTATION SYSTEMS, LLC

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Company Details

Name: ADVANCED CYTOMETRY INSTRUMENTATION SYSTEMS, LLC
Jurisdiction: New York
Legal type: DOMESTIC LIMITED LIABILITY COMPANY
Status: Active
Date of registration: 26 Jul 2001 (24 years ago)
Entity Number: 2664416
ZIP code: 14120
County: Erie
Place of Formation: New York
Address: 7342 PADDOCK RIDGE, PENDLETON, NY, United States, 14120

DOS Process Agent

Name Role Address
DANIEL CARO DOS Process Agent 7342 PADDOCK RIDGE, PENDLETON, NY, United States, 14120

Unique Entity ID

A UEI is a government-provided number, like a tax ID number, that’s used to identify businesses eligible for federal grants, awards and contracts.

Note: In April 2022, the federal government replaced its old identifier of choice, the Data Universal Numbering System (DUNS) number, with a government-issued UEI. Now all the federal government’s Integrated Award Environment systems use UEI numbers instead of DUNS numbers. So any entity doing business with the federal government must register for a UEI.

Unique Entity ID:
YLGMJXLP7TW5
CAGE Code:
3A1W0
UEI Expiration Date:
2025-10-11

Business Information

Doing Business As:
ACIS
URL:
http://acis-us.com
Activation Date:
2024-10-15
Initial Registration Date:
2002-08-15

Commercial and government entity program

The The Commercial And Government Entity Code (CAGE) is assigned by the Department of Defense's Defense Logistics Agency (DLA) and represents your company's physical address for GSA's mailings, payments, and administrative records.

Note: A CAGE Code enables a company to contract with the U.S. government, allowing bid on government contracts and to receive government payments. Also for business this means that it's a Verified business entity and Has a validated physical address.

CAGE number:
3A1W0
Status:
Obsolete
Type:
Non-Manufacturer
CAGE Update Date:
2024-10-15
SAM Expiration:
2025-10-11

Contact Information

POC:
ANDREY KUZMIN
Corporate URL:
http://acis-us.com

History

Start date End date Type Value
2001-07-26 2008-01-08 Address 3400 HSBC CENTER, BUFFALO, NY, 14203, USA (Type of address: Service of Process)

Filings

Filing Number Date Filed Type Effective Date
090730003380 2009-07-30 BIENNIAL STATEMENT 2009-07-01
080108002467 2008-01-08 BIENNIAL STATEMENT 2007-07-01
050725002068 2005-07-25 BIENNIAL STATEMENT 2005-07-01
030722002104 2003-07-22 BIENNIAL STATEMENT 2003-07-01
011010000834 2001-10-10 AFFIDAVIT OF PUBLICATION 2001-10-10

USAspending Awards / Contracts

Procurement Instrument Identifier:
75D30123P16135
Link:
View Award on USAspending website
Award Or Idv Flag:
AWARD
Award Type:
PURCHASE ORDER
Action Obligation:
9980.00
Base And Exercised Options Value:
9980.00
Base And All Options Value:
9980.00
Awarding Agency Name:
Department of Health and Human Services
Performance Start Date:
2023-04-20
Description:
LAB SUPPLIES
Naics Code:
541990: ALL OTHER PROFESSIONAL, SCIENTIFIC, AND TECHNICAL SERVICES
Product Or Service Code:
6640: LABORATORY EQUIPMENT AND SUPPLIES

USAspending Awards / Financial Assistance

Date:
2022-09-22
Link:
View on USAspending
Awarding Agency Name:
Department of Health and Human Services
Transaction Description:
SMART PHOTODYNAMIC THERAPY FOR ACNE BY REVERSIBLY SWITCHABLE INTERSYSTEM CROSSING IN PURE ORGANIC MATERIALS - ABSTRACT – ACNE VULGARIS IS THE MOST COMMON SKIN CONDITION IN THE UNITED STATES, AFFECTING UP TO 50 MILLION AMERICANS ANNUALLY. WHILE ACNE IS COMMON IN YOUNG PEOPLE, THIS CONDITION BECOMES INCREASINGLY WIDESPREAD IN ADULTS, ESPECIALLY IN FEMALES— CHRONIC POST-ADOLESCENT ACNE AFFECTS ABOUT 15 PERCENT OF WOMEN IN THE USA. MODERATE TO SEVERE ACNE CONFERS A TREMENDOUS MEDICAL, PSYCHOLOGICAL, AND ECONOMIC HEALTH CARE BURDEN ON THE US POPULATION. THE DEVELOPMENT OF ACNE IS MULTIFACTORIAL, BUT CENTERS AROUND THE SEBACEOUS GLANDS (SG), WHICH ARE THE MICROSCOPIC HOLOCRINE GLANDS WITHIN THE SKIN DERMIS. SGS COMPRISE SPECIALIZED CELLS—SEBOCYTES—THAT SECRETE A VARIETY OF LIPIDS COMPOSING THE SEBUM. CONVENTIONAL CLINICAL TREATMENT OF SEVERE INFLAMMATORY ACNE INVOLVES A COMBINATION OF TOPICAL AND SYSTEMIC DRUGS, ADMINISTERED OVER THE COURSE OF SEVERAL MONTHS OR EVEN YEARS. THESE INCLUDE TOPICAL AND ORAL RETINOIDS, ANTIBIOTICS, AND IN SOME INSTANCES, HORMONAL THERAPY. TREATMENT IS OFTEN INEFFECTIVE AND CARRIES THE RISK OF ADVERSE SIDE EFFECTS. REMARKABLY, PHOTODYNAMIC THERAPY (PDT) HAS SHOWN BREAKTHROUGH POTENTIAL FOR DERMATOLOGY. PDT INVOLVES TOPICAL APPLICATION OF AGENTS CALLED PHOTOSENSITIZERS (PS) TO THE AFFECTED SKIN AREA. WHEN EXPOSED TO SPECIFIC WAVELENGTHS OF LIGHT, THESE AGENTS GENERATE HIGHLY CYTOTOXIC SINGLET OXYGEN (1O2 ) THAT DAMAGES SEBOCYTES, REDUCING BOTH THE SIZE AND ACTIVITY OF SGS, AND LOCALLY ELIMINATES BACTERIAL INFECTIONS. HOWEVER, USE OF CONVENTIONAL PDT INCLUDES A SIGNIFICANT RISK OF SKIN DAMAGE AS THE 1O2 INHERENTLY DAMAGES FIBROBLASTS, EPITHELIUM, AND OTHER SKIN COMPONENTS OUTSIDE THE SG IN THE ENTIRE IRRADIATED SKIN AREA. THE UNINTENDED PHOTODAMAGE HAS AN ADVERSE EFFECT ON SKIN STRUCTURE AND FUNCTION AND CAN POTENTIALLY LEAD TO CANCER. THUS, THE UTILITY OF CONVENTIONAL PDT IS LIMITED BECAUSE OF THESE SIGNIFICANT SIDE EFFECTS. TO ADDRESS THIS LIMITATION, ACIS IS DEVELOPING A SMART PDT (S-PDT) PLATFORM WILL ENABLE TARGETED AND TUNABLE TREATMENT TO CELLS OF THE SGS, WHILE SPARING OTHER CELL TYPES. AS PART OF THIS, ACIS IS DEVELOPING A NEXT GENERATION PS AGENT THAT IS DESIGNED TO BE ACTIVE SELECTIVELY IN THE SEBUM PRODUCING CELLS OF SGS AND BACTERIA-INFECTED SITES, WHILE CAUSING NO DAMAGE TO THE SURROUNDING HEALTHY TISSUE. THIS APPROACH ALLEVIATES THE COMMON PHOTODYNAMIC THERAPY LIMITATIONS VIA REVERSIBLE ON/OFF SWITCHING OF INTERSYSTEM CROSSING IN SMALL ORGANIC MOLECULES, THEREBY BOOSTING (IN “ON” MODE) OR SUPPRESSING (IN “OFF” MODE) SINGLET OXYGEN PRODUCTION. THE SPECIFIC AIMS OF THIS PHASE I PROJECT ARE AS FOLLOWS : 1) DESIGN AND SYNTHESIZE A REVERSIBLY SWITCHABLE PH-SENSITIVE PS WITH TUNABLE ISOELECTRIC POINT AND TUNABLE ABSORPTION MAXIMUM TO PENETRATE THE SKIN AT THE OPTIMAL DEPTH; AND 2) DEMONSTRATE THE VIABILITY OF THE S-PDT APPROACH VIA IN VITRO AND EX VIVO TESTS, INCLUDING CELLULAR UPTAKE, CYTOTOXICITY, AND PDT ACTION OF NEWLY SYNTHESIZED MATERIALS IN HUMAN SKIN MODELS. SUCCESSFUL COMPLETIONS OF THESE AIMS WILL DEMONSTRATE THE VIABILITY OF THE S-PDT PLATFORM AND SUPPORT FURTHER DEVELOPMENT IN PHASE II.
Obligated Amount:
258586.88
Face Value Of Loan:
0.00
Total Face Value Of Loan:
0.00
Date:
2018-08-31
Link:
View on USAspending
Awarding Agency Name:
Department of Health and Human Services
Transaction Description:
NOVEL OPTICAL DENTAL IMAGING TECHNOLOGY UTILIZING TARGETED UPCONVERSION NANOPARTICLES FOR NONINVASIVE DETECTION OF DENTAL CARIES
Obligated Amount:
198724.36
Face Value Of Loan:
0.00
Total Face Value Of Loan:
0.00
Date:
2017-09-14
Link:
View on USAspending
Awarding Agency Name:
Department of Health and Human Services
Transaction Description:
NOVEL SINGLE CELL ASSAY FOR QUANTITATIVE ANALYSIS OF CELL HETEROGENEITY BY NONINVASIVE PROBING OF MOLECULAR COMPOSITION OF SPECIFIC ORGANELLES IN INDIVIDUAL CELLS
Obligated Amount:
1193706.00
Face Value Of Loan:
0.00
Total Face Value Of Loan:
0.00
Date:
2016-03-17
Link:
View on USAspending
Awarding Agency Name:
Department of Health and Human Services
Transaction Description:
NOVEL SINGLE CELL ASSAY FOR QUANTITATIVE ANALYSIS OF CELL HETEROGENEITY BY NONINVASIVE PROBING OF MOLECULAR COMPOSITION OF SPECIFIC ORGANELLES IN IND
Obligated Amount:
147725.00
Face Value Of Loan:
0.00
Total Face Value Of Loan:
0.00

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7342 PADDOCK RIDGE, PENDLETON, NY, United States, 14120

CYC TECHNOLOGY GROUP INC.

Date of last update: 30 Mar 2025

Sources: New York Secretary of State

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