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  5. LITRON LABORATORIES LTD.

LITRON LABORATORIES LTD.

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Company Details

Name: LITRON LABORATORIES LTD.
Jurisdiction: New York
Legal type: DOMESTIC BUSINESS CORPORATION
Status: Active
Date of registration: 05 Oct 1976 (49 years ago)
Entity Number: 411608
ZIP code: 14623
County: Monroe
Place of Formation: New York
Address: 3500 WINTON PLACE, SUITE 1B, ROCHESTER, NY, United States, 14623

Shares Details

Shares issued 200

Share Par Value 0

Type NO PAR VALUE

DOS Process Agent

Name Role Address
THE CORPORATION DOS Process Agent 3500 WINTON PLACE, SUITE 1B, ROCHESTER, NY, United States, 14623

Chief Executive Officer

Name Role Address
CAROL R TOMETSKO-LITRON Chief Executive Officer 3500 WINTON PLACE, SUITE 1B, ROCHESTER, NY, United States, 14623

Unique Entity ID

Unique Entity ID:
LJH7LE9AUHL5
CAGE Code:
0WSM9
UEI Expiration Date:
2026-02-28

Business Information

URL:
http://www.LitronLabs.com
Activation Date:
2025-03-04
Initial Registration Date:
2001-05-24

Commercial and government entity program

CAGE number:
0WSM9
Status:
Active
Type:
Non-Manufacturer
CAGE Update Date:
2025-03-04
CAGE Expiration:
2030-03-04
SAM Expiration:
2026-02-28

Contact Information

POC:
DREW TOMETSKO
Corporate URL:
http://www.litronlabs.com

Form 5500 Series

Employer Identification Number (EIN):
161080732
Plan Year:
2024
Number Of Participants:
19
Sponsors Telephone Number:
5854420930
File:
View File
Plan Year:
2023
Number Of Participants:
17
Sponsors Telephone Number:
5854420930
File:
View File
Plan Year:
2022
Number Of Participants:
17
Sponsors Telephone Number:
5854420930
File:
View File
Plan Year:
2021
Number Of Participants:
19
Sponsors Telephone Number:
5854420930
File:
View File
Plan Year:
2020
Number Of Participants:
19
Sponsors Telephone Number:
5854420930
File:
View File

History

Start date End date Type Value
2024-11-14 2024-11-14 Address 3500 WINTON PLACE, SUITE 1B, ROCHESTER, NY, 14623, USA (Type of address: Chief Executive Officer)
2024-11-14 2024-11-14 Address 1351 MT HOPE AVE, #207, ROCHESTER, NY, 14620, USA (Type of address: Chief Executive Officer)
2022-02-09 2024-11-14 Shares Share type: NO PAR VALUE, Number of shares: 200, Par value: 0
2021-08-17 2022-02-09 Shares Share type: NO PAR VALUE, Number of shares: 200, Par value: 0
2002-10-09 2024-11-14 Address 1351 MT HOPE AVE, #207, ROCHESTER, NY, 14620, USA (Type of address: Chief Executive Officer)

Filings

Filing Number Date Filed Type Effective Date
241114000617 2024-11-14 BIENNIAL STATEMENT 2024-11-14
20110223037 2011-02-23 ASSUMED NAME CORP INITIAL FILING 2011-02-23
050131002070 2005-01-31 BIENNIAL STATEMENT 2004-10-01
021009002124 2002-10-09 BIENNIAL STATEMENT 2002-10-01
001013002142 2000-10-13 BIENNIAL STATEMENT 2000-10-01

USAspending Awards / Contracts

Procurement Instrument Identifier:
75F40124P00236
Link:
View Award on USAspending website
Award Or Idv Flag:
AWARD
Award Type:
PURCHASE ORDER
Action Obligation:
98492.00
Base And Exercised Options Value:
98492.00
Base And All Options Value:
98492.00
Awarding Agency Name:
Department of Health and Human Services
Performance Start Date:
2024-08-12
Description:
PIG-A MUTATION FREQUENCY ASSAYS
Naics Code:
541380: TESTING LABORATORIES AND SERVICES
Product Or Service Code:
6640: LABORATORY EQUIPMENT AND SUPPLIES
Procurement Instrument Identifier:
75F40124P00018
Link:
View Award on USAspending website
Award Or Idv Flag:
AWARD
Award Type:
PURCHASE ORDER
Action Obligation:
24744.00
Base And Exercised Options Value:
24744.00
Base And All Options Value:
24744.00
Awarding Agency Name:
Department of Health and Human Services
Performance Start Date:
2024-05-17
Description:
LITRON IN-VITRO MICROFLOW ASSAY KITS, QTY 6
Naics Code:
334516: ANALYTICAL LABORATORY INSTRUMENT MANUFACTURING
Product Or Service Code:
6640: LABORATORY EQUIPMENT AND SUPPLIES
Procurement Instrument Identifier:
75F40122P00364
Link:
View Award on USAspending website
Award Or Idv Flag:
AWARD
Award Type:
PURCHASE ORDER
Action Obligation:
16959.00
Base And Exercised Options Value:
16959.00
Base And All Options Value:
16959.00
Awarding Agency Name:
Department of Health and Human Services
Performance Start Date:
2022-08-16
Description:
MICROFLOW AND MULTI-FLOW IN VITRO KITS
Naics Code:
325414: BIOLOGICAL PRODUCT (EXCEPT DIAGNOSTIC) MANUFACTURING
Product Or Service Code:
6550: IN VITRO DIAGNOSTIC SUBSTANCES, REAGENTS, TEST KITS AND SETS

USAspending Awards / Financial Assistance

Date:
2024-08-09
Link:
View on USAspending
Awarding Agency Name:
Department of Health and Human Services
Transaction Description:
DEVELOPMENT OF A COMPREHENSIVE HEN'S EGG MODEL FOR GENOTOXICITY TESTING - PROJECT SUMMARY PHARMACEUTICALS AND VARIOUS INDUSTRIAL CHEMICALS UNDERGO COMPREHENSIVE TOXICOLOGICAL ASSESSMENT IN ORDER TO SAFEGUARD HUMAN HEALTH. GENETIC TOXICOLOGY IS A KEY COMPONENT OF THIS RISK ASSESSMENT. THIS TESTING EVALUATES CHEMICALS FOR THEIR POTENTIAL TO DAMAGE DNA, AN INTEGRAL FACTOR IN THE DEVELOPMENT OF CANCER AND OTHER DISEASES. FOR DECADES, IN VIVO ASSAYS HAVE GUIDED GENOTOXIC RISK ASSESSMENT DUE TO THEIR ABILITY TO MIRROR PHYSIOLOGICAL RESPONSES IN HUMANS. THEIR ENDOGENOUS METABOLISM PROVIDES THE ENZYMATIC ACTIVATION NECESSARY FOR GENERATING GENOTOXIC INTERMEDIATES, MANY OF WHICH ARE DIFFICULT TO DETECT WITH IN VITRO ASSAYS. ADDITIONALLY, THEIR COMPLETE ORGAN SYSTEMS PROVIDE THE STRUCTURE FOR IDENTIFYING ORGAN SPECIFIC GENOTOXICITY, ESPECIALLY EFFECTS IN LIVER AND BLOOD. LEADING IN VIVO ASSAYS INCLUDE THE MAMMALIAN MICRONUCLEUS ASSAY, COMET ASSAY, CHROMOSOMAL ABERRATION ASSAYS, AND RODENT-BASED MUTATIONAL ASSAYS. WHILE THESE HAVE SERVED AS A PILLAR OF GENOTOXIC RISK ASSESSMENT, REGULATORY AGENCIES WORLDWIDE HAVE BEGUN TO RESTRICT AND EVEN ELIMINATE THE USE OF ANIMALS IN TOXICOLOGY RESEARCH. THIS SIGNIFICANT SHIFT IN RISK ASSESSMENT HAS LEFT THE FIELD OF GENETIC TOXICOLOGY IN NEED OF A NON-ANIMAL, METABOLICALLY-ACTIVE SYSTEMS THAT EFFECTIVELY MODELS GENOTOXIC RISK IN HUMANS. IN VITRO ASSAYS PROVIDE INITIAL INSIGHT INTO GENOTOXIC RISK, BUT MANY LACK ENDOGENOUS METABOLIC ACTIVATION OR ONLY FOCUS ON INDIVIDUAL CELL TYPES/ORGANS. WE WILL ADDRESS THE PRESSING NEED FOR AN EFFECTIVE IN VITRO GENOTOXICITY ASSAY THROUGH OUR DEVELOPMENT OF A COMPREHENSIVE HEN’S EGG MODEL FOR GENOTOXIC ANALYSIS. THE HEN’S EGG IS A UNIQUE SYSTEM IN THAT IT IS NOT CONSIDERED AN ANIMAL MODEL DUE TO DEFICIENCIES IN BRAIN ACTIVITY AND PAIN PERCEPTION EARLY IN DEVELOPMENT. YET, SIMILAR TO IN VIVO MODELS, THE HEN’S EGG HAS ENDOGENOUS METABOLIC ACTIVITY AND FUNCTIONING HEPATIC AND HEMOPOIETIC ORGAN SYSTEMS. WE WILL LEVERAGE THESE FEATURES TO DEVELOP AN ASSAY THAT SIMULTANEOUSLY EVALUATES GENOTOXICITY IN THE BLOOD AND LIVER. OUR UTILIZATION OF FLOW CYTOMETRY AND HIGH CONTENT IMAGING WILL AUTOMATE MICRONUCLEI QUANTIFICATION IN THE ERYTHROCYTES AND HEPATOCYTES. FURTHERMORE, WE WILL INCORPORATE THE ASSESSMENT OF GENOTOXIC AND CYTOTOXIC BIOMARKERS, PROVIDING VALUABLE INSIGHT INTO ORGAN SPECIFIC TOXICITY AND GENOTOXIC MODE OF ACTION. THE DEVELOPMENT, OPTIMIZATION AND VALIDATION OF OUR HEN’S EGG GENOTOXICITY ASSAY WILL MEET THE CRITICAL NEED FOR AN ACCURATE, METABOLICALLY-ACTIVE IN VITRO GENOTOXICITY ASSAY, WHILE FULFILLING UPCOMING REGULATORY REQUIREMENTS.
Obligated Amount:
295734.00
Face Value Of Loan:
0.00
Total Face Value Of Loan:
0.00
Date:
2023-07-14
Link:
View on USAspending
Awarding Agency Name:
Department of Health and Human Services
Transaction Description:
MODELING THE RESPONSIVENESS OF SENSITIVE POPULATIONS TO GENOTOXIC AGENTS USING DNA REPAIR INHIBITORS - PROJECT SUMMARY IT IS WELL RECOGNIZED THAT CONVENTIONAL TOXICOLOGY ASSAYS EXHIBIT A CRUCIAL DEFICIENCY. SPECIFICALLY, THEIR USE OF LIMITED NUMBERS OF CELL LINES AND RODENT STRAINS DOES NOT PROVIDE INFORMATION ABOUT TOXIC RESPONSES THAT MAY OCCUR IN SENSITIVE HUMAN POPULATIONS. ALTHOUGH STUDYING VERY LARGE NUMBERS OF CELL LINES AND LABORATORY RODENT MODELS COULD THEORETICALLY ADDRESS THIS ISSUE, IT IS NOT A PRACTICAL ANSWER. THERE ARE SIMPLY TOO MANY LEGACY CHEMICALS AND NEW CHEMICAL SUBSTANCES BEING DEVELOPED FOR THIS TO REPRESENT A ROUTINE TESTING SCHEME. FORTUNATELY, IN THE AREA OF GENETIC TOXICOLOGY, A SOLUTION EXISTS. OUR INNOVATIVE APPROACH TAKES INTO ACCOUNT THE FACT THAT INTER-SUBJECT DIFFERENCES IN SENSITIVITY TO GENOTOXIC AGENTS IS PREDOMINATELY DUE TO VARIABLE DNA REPAIR CAPACITY. OUR PROJECT WILL DEVELOP AN EFFICIENT, HIGH THROUGHPUT, IN VITRO GENOTOXICITY ASSAY PLATFORM THAT PROVIDES INFORMATION ABOUT CHEMICALS’ POTENTIAL TO CAUSE DNA DAMAGE IN PROTOTYPICAL AND SENSITIVE HUMAN POPULATIONS. THE HIGH EFFICIENCY OF OUR PROPOSED APPROACH IS IN PART EXPLAINED BY OUR DECISION TO STUDY A SINGLE P53- COMPETENT HUMAN CELL LINE (TK6) TO GENERATE PROTOTYPICAL GENOTOXIC RESPONSE PROFILES. SENSITIVE POPULATION RESPONSES WILL BE MODELLED BY CO-EXPOSING CELLS TO EACH TEST CHEMICAL IN COMBINATION WITH A PANEL OF SMALL MOLECULE DNA REPAIR INHIBITORS. THESE INHIBITORS WILL BE CHOSEN TO COVER EACH OF THE MAJOR DNA REPAIR PATHWAYS. IN ADDITION TO OUR USE OF DNA REPAIR INHIBITORS TO EFFICIENTLY MIMIC SENSITIVE POPULATIONS, OTHER INNOVATIVE ASPECTS OF OUR PROJECT INCLUDE OUR USE OF A MULTIPLEXED DNA DAMAGE ASSAY TO COVER MULTIPLE BIOMARKERS OF GENOTOXICITY AND CYTOTOXICITY, AND STATE-OF-THE-ART BENCHMARK DOSE SOFTWARE TO CHARACTERIZE THE FAMILY OF DOSE-RESPONSE RELATIONSHIPS THAT WILL BE GENERATED FOR EACH CHEMICAL STUDIED. ONCE REDUCED TO PRACTICE, WE WILL MAKE THE ASSAY AVAILABLE AS A SET OF KIT-FORMATTED REAGENTS, AND ALSO THROUGH FEE-FOR-SERVICE TESTING.
Obligated Amount:
230278.00
Face Value Of Loan:
0.00
Total Face Value Of Loan:
0.00
Date:
2021-04-02
Link:
View on USAspending
Awarding Agency Name:
Department of Health and Human Services
Transaction Description:
HIGH THROUGHPUT SCREEN AND HIGH INFORMATION FOLLOW-UP TESTS FOR GENOTOXICANTS - PROJECT SUMMARY CURRENT BATTERIES OF GENETIC TOXICOLOGY ASSAYS EXHIBIT SEVERAL CRITICAL DEFICIENCIES. FIRST, THE THROUGHPUT CAPACITY OF IN VITRO GENOTOXICITY TESTS IS LOW, AND DOES NOT MEET CURRENT NEEDS, ESPECIALLY FOR EARLY, HIGH VOLUME SCREENING ENVIRONMENTS THAT NEED TO PRIORITIZE CHEMICALS FOR FURTHER TESTING AND/OR DEVELOPMENT. SECOND, CONVENTIONAL ASSAYS PROVIDE SIMPLISTIC BINARY CALLS, GENOTOXIC OR NON-GENOTOXIC. IN THIS SCHEME THERE IS LITTLE OR NO INFORMATION PROVIDED ABOUT GENOTOXIC MODE OF ACTION. THIS IS SEVERELY LIMITING, AS IT DOES NOT GENERATE KEY INFORMATION NECESSARY FOR PRIORITIZING CHEMICALS FOR FURTHER TESTING, GUIDING SUBSEQUENT ASSAYS’ ENDPOINTS/EXPERIMENTAL DESIGNS, OR CONDUCTING RISK ASSESSMENTS. FINALLY, MOST CURRENT ASSAYS DO NOT PLACE REQUISITE EMPHASIS ON DOSE RESPONSE RELATIONSHIPS, AND THEREFORE DO NOT CONTEXTUALIZE THE RESULTS IN TERMS OF POTENCY. THESE DEFICIENCIES PREVENT GENOTOXICITY DATA FROM OPTIMALLY CONTRIBUTING TO MODERN RISK ASSESSMENTS, WHERE ALL OF THESE CAPABILITIES AND HIGH INFORMATION CONTENT ARE ESSENTIAL. WE WILL SOLVE THESE ISSUES BY DEVELOPING, OPTIMIZING, AND VALIDATING A TWO-TIERED TESTING STRATEGY BASED ON MULTIPLEXED DNA DAMAGE RESPONSIVE BIOMARKERS AND HIGH-SPEED FLOW CYTOMETRIC ANALYSIS. THE FIRST-TIER FOCUSES ON THROUGHPUT AND IS USED TO PRIORITIZE LIKELY GENOTOXICANTS FOR MORE COMPREHENSIVE ANALYSIS IN SECOND TIER TESTING. SPECIFICALLY, IT INVOLVES A COLLECTION OF SEVERAL MULTIPLEXED BIOMARKERS THAT WILL BE USED TO IDENTIFY LIKELY GENOTOXIC AGENTS AND PROVIDE A PRELIMINARY ASSESSMENT OF GENOTOXIC MODE OF ACTION. THE GH2AX BIOMARKER DETECTS DNA DOUBLE STRAND BREAKS, PHOSPHO-HISTONE H3 IDENTIFIES MITOTIC CELLS, NUCLEAR P53 CONTENT REPORTS ON P53 ACTIVATION IN RESPONSE TO DNA DAMAGE, THE FREQUENCY OF 8N+ CELLS MEASURE POLYPLOIDIZATION, AND THE RATIO OF NUCLEI TO MICROSPHERE COUNTS PROVIDES INFORMATION ABOUT TREATMENT-RELATED CYTOTOXICITY. THE SECOND TIER FOCUSES ON INFORMATION CONTENT AND CONSIDERS MANY MORE CONCENTRATIONS AS WELL AS ADDITIONAL BIOMARKERS, INCLUDING MICRONUCLEUS FORMATION. COLLECTIVELY, THE TIER TWO RESULTS PROVIDE DEFINITIVE PREDICTIONS ABOUT TEST CHEMICALS’ GENOTOXIC POTENTIAL, MODE OF ACTION, AND POTENCY. OVER THE COURSE OF THIS PROJECT WE WILL STUDY MORE THAN 3,000 DIVERSE CHEMICALS IN ORDER TO UNDERSTAND THE PERFORMANCE CHARACTERISTICS AND GENERALIZABILITY OF THE TWO-TIERED TESTING STRATEGY. AN INTERLABORATORY TRIAL WILL BE CONDUCTED WITH PROTOTYPE ASSAY KITS TO ASSESS THE TRANSFERABILITY OF THE METHODS, WITH THE ULTIMATE GOAL OF PROVIDING THE NATION WITH COMMERCIALLY AVAILABLE KITS AND TESTING SERVICES.
Obligated Amount:
1832396.00
Face Value Of Loan:
0.00
Total Face Value Of Loan:
0.00
Date:
2020-09-25
Link:
View on USAspending
Awarding Agency Name:
Department of Health and Human Services
Transaction Description:
DEVELOPMENT OF RAT LIVER 3D ORGANOID METHODS TO ADDRESS GENOTOXICITY SCREENING
Obligated Amount:
149504.19
Face Value Of Loan:
0.00
Total Face Value Of Loan:
0.00
Date:
2020-04-13
Link:
View on USAspending
Awarding Agency Name:
Small Business Administration
Transaction Description:
TO AID SMALL BUSINESSES IN MAINTAINING WORK FORCE DURING COVID-19 PANDEMIC.
Obligated Amount:
0.00
Face Value Of Loan:
190950.00
Total Face Value Of Loan:
190950.00

Trademarks Section

Serial Number:
86654411
Mark:
MULTIFLOW
Status:
SECTION 8 & 15-ACCEPTED AND ACKNOWLEDGED
Mark Type:
TRADEMARK
Application Filing Date:
2015-06-08
Mark Drawing Type:
Standard character mark
Mark Literal Elements:
MULTIFLOW
USPTO Link:
View Trademark Status and Document Retrieval (TSDR)

Goods And Services

For:
Scientific research kits comprising chemical solutions, enzymes, dyes, and antibodies for lysing eukaryotic cells and analyzing cells
First Use:
2015-10-13
International Classes:
001 - Primary Class
Class Status:
Active
Serial Number:
85033214
Mark:
MUTAFLOW
Status:
REGISTERED AND RENEWED
Mark Type:
TRADEMARK
Application Filing Date:
2010-05-07
Mark Drawing Type:
Standard character mark
Mark Literal Elements:
MUTAFLOW
USPTO Link:
View Trademark Status and Document Retrieval (TSDR)

Goods And Services

For:
Scientific research kits comprising chemical solutions, immunological reagents, dyes, and templates for recording results, for the purpose of analyzing cells
International Classes:
001 - Primary Class
Class Status:
Active
Serial Number:
77391490
Mark:
MICROFLOW
Status:
REGISTERED AND RENEWED
Mark Type:
TRADEMARK
Application Filing Date:
2008-02-07
Mark Drawing Type:
Standard character mark
Mark Literal Elements:
MICROFLOW
USPTO Link:
View Trademark Status and Document Retrieval (TSDR)

Goods And Services

For:
Scientific research kits comprising chemical solutions, dye, and a template for recording results, for the purpose of analyzing cells
International Classes:
001 - Primary Class
Class Status:
Active
Serial Number:
75717611
Mark:
MICROFLOW
Status:
REGISTERED AND RENEWED
Mark Type:
SERVICE MARK
Application Filing Date:
1999-05-28
Mark Drawing Type:
Typeset: Word(s)/letter(s)/number(s)
Mark Literal Elements:
MICROFLOW
USPTO Link:
View Trademark Status and Document Retrieval (TSDR)

Goods And Services

For:
Laboratory testing services for detecting the presence of micronucleated blood cells in blood or bone marrow samples based on flow cytometry
First Use:
1998-12-31
International Classes:
042 - Primary Class
Class Status:
Active
Serial Number:
75717610
Mark:
MICROFLOW
Status:
REGISTERED AND RENEWED
Mark Type:
TRADEMARK
Application Filing Date:
1999-05-28
Mark Drawing Type:
Illustration: Drawing with word(s)/letter(s)/number(s) in Stylized form
Mark Literal Elements:
MICROFLOW
USPTO Link:
View Trademark Status and Document Retrieval (TSDR)

Goods And Services

For:
Scientific research kits comprising fixative, anticoagulant, [ razor blades,] vials and tubes, and written instructions, all for preparing blood or bone marrow samples for subsequent flow cytometric analysis to detect the presence of micronucleated blood cells
First Use:
1997-11-10
International Classes:
009 - Primary Class
Class Status:
Active

Paycheck Protection Program

Jobs Reported:
14
Initial Approval Amount:
$190,950
Date Approved:
2020-04-13
Loan Status:
Paid in Full
SBA Guaranty Percentage:
100
Current Approval Amount:
$190,950
Race:
Unanswered
Ethnicity:
Unknown/NotStated
Gender:
Unanswered
Veteran:
Unanswered
Forgiveness Amount:
$192,409.59
Servicing Lender:
Manufacturers and Traders Trust Company
Use of Proceeds:
Payroll: $152,760
Utilities: $3,356
Rent: $6,061
Healthcare: $28773

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Date of last update: 18 Mar 2025

Sources: New York Secretary of State

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